Treating Skin Hyperpigmentation with Niacinamide

Written by Dr. Naeemah Ruffin

Our skin functions as a barrier to protect our body from external harmful factors, prevent water loss from the body, and regulates our body temperature.1 However, factors such as UV radiation which causes photoaging, free radicals, and pollution can cause inflammation in our skin resulting in dark spots, or hyperpigmentation3, which is a common reason people visit dermatologists.2

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While there are many treatments to address skin hyperpigmentation such as hydroquinone, a popular skin bleaching agent, many individuals seek skincare products with more natural ingredients. Research over the past decade has led to the discovery of several naturally occurring ingredients to lighten dark areas of the skin and these ingredients are increasing in popularity.2

 Niacinamide has been found to be effective at lightening dark spots when applied topically.  It has been used in cosmetics for decades to brighten skin tone and prevent skin aging.1 Niacinamide is an active form of vitamin B3 (niacin) found in yeast, root vegetables, brown rice, nuts, seeds, and legumes and is primarily used as a nutritional supplement.2

It’s pharmaceutical and cosmeceutical uses have been extensively researched and many studies on niacinamide have highlighted its ability to prevent and treat hyperpigmentation.1 Niacinamide works by inhibiting the transfer of melanin to cells in the upper layer of the skin 2 and studies show that when products containing niacinamide are applied to hyperpigmented areas, a skin-lightening effect can occur.1

Topical nicotinamide is well tolerated by the skin and studies show that using Niacinamide at effective concentration levels in a moisturizer can reveal results in about 8 weeks of treatment.1 Also, it has been shown that nicotinamide and hydroquinone have comparable skin depigmenting activity.1

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Clinical trials have shown additional benefits of Niacinamide use as an anti-aging agent that can improve the looks of wrinkles and increase skin elasticity. This antiaging effect is increased when sunscreen with a sun protection factor (SPF) of 30 is added to the skincare regimen.1

Clinical trials have shown that topical treatment of nicotinamide can be used alone or in combination with other active ingredients to slow the progression of skin aging and hyperpigmentation.1 For example, since nicotinamide plays a role in inhibiting melanin post synthesis, combining it with other active ingredients that play different roles such as inhibiting melanin during synthesis would maximize the effect. Among ingredients on this list are azelaic acid and arbutin.4

Bellantz is pleased to offer our newest product addition to our skincare line, Niacinamide Radiance Crème. This lightweight daily crème promotes natural radiance through its revitalizing cocktail of Niacinamide along with Azelaic Acid, Arbutin, Kojic Acid and Vitamin C. Our crème also contains a nutrient-rich complex of natural humectants that protect against environmental stressors that cause dry, dull looking skin. To learn more, click here.


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